ESSDAI Trajectory (Disease Activity)
ESSPRI Trajectory (Symptom Burden)
2. Organ Domain Activity (Heatmap)
3. Clinical Trajectory (Snail Plot)
Inflammation vs. Symptoms
4a. Serology (IgG & RF)
4b. Complement Consumption (C3 & C4)
5. Performance to Target
6. Multi-Parametric Phenotype (Month 0)
Lymphoma Risk Stratification
Fragkioudaki Score (0-7) + Dynamic Activity
Absolute Risk Estimate
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Calculating...
Baseline Predictors (Fragkioudaki)
Parotid
Lymphadenopathy
Raynaud's
Anti-Ro/La
RF Positive
Mono. Gammopathy
Low C4
Dynamic Risk (Disease Activity)
ESSDAI ≥ 5 (OR 3.88)
High Risk Domains: None
7. Systemic Defense Shield (Screening Status)
Lymphoma
Labs, Parotid Exam
Overdue
Lung (ILD)
PFTs, HRCT
Overdue
Vasculitis
Skin, Complement
Overdue
Renal (Kidney)
UA, Creatinine
Overdue
⚠️ Monitoring Gap: Screening steps incomplete.
© Brandon Law
The tool is for educational use only, is not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment. Risk model based on Fragkioudaki et al.